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Live long enough and you can pretty much count on
developing arthritis: a touch of osteoarthritis, at the very least.
Arthritis ('arth' meaning joint, 'itis' meaning inflammation) isn't
a one-note story or even a few variations on a single theme; it actually
consists of more than 100 different conditions. These can be anything from
relatively mild forms of tendinitis (as in 'tennis elbow') and bursitis to
crippling systemic forms, such as rheumatoid arthritis. There are pain syndromes
like fibromyalgia and arthritis-related disorders, such as systemic lupus
erythematosus, that involve every part of the body. There are forms of the
disease, such as gout, that almost nobody connects with arthritis, and there are
other conditions - like osteoarthritis, the misnamed 'wear and tear' arthritis -
that a good many people think is the only form of the disease.
True, many
older people do have arthritis, but it's not just a disease of the old. Some
forms of arthritis affect children still in diapers, while thousands of people
are stricken in the prime of their lives. The common denominator for all these
conditions is joint and musculoskeletal pain, which is why they are grouped
together as 'arthritis.' Often that pain is a result of inflammation of the
joint lining.
Inflammation is involved in many forms of arthritis. It is
the body's natural response to injury. The warning signs that inflammation
presents are redness, swelling, heat and pain. These are the same kinds of
reaction the body has to a sliver in the hand, for example. When a joint becomes
inflamed, it may get any or all of these symptoms. This can prevent the normal
use of the joint and therefore it can cause the loss of function of that
joint.
Anatomy of a
Joint
There are more than 100 joints connecting the body's 206 bones. Most
of the major bone connections in the body are joints designed to allow a broad
range of motion. There are different kinds for different functions: ball-and-socket
(hips and shoulders), saddle joints (which connect thumb to hand), hinge joints (fingers
and knees) or pivot joints (wrists).
Tied together by ligaments, the bones of
joints are capped with a smooth substance called cartilage. This tough elastic
material acts as a shock absorber and allows the bone ends to glide smoothly
across each other. If the cartilage is destroyed (as in osteoarthritis), the
bones of a joint can grind against each other causing pain, loss of mobility,
deformity and dysfunction.
Between the bones is a joint cavity, which
gives the bones room to move. The joint space between two bones is enclosed by a
capsule that's flexible, yet strong enough to protect the joint against
dislocation. The inner lining of this capsule, the synovium, produces a thick
fluid that lubricates and nourishes the joint. In many forms of arthritis, the
synovium becomes inflamed and thickened, producing extra fluid which contains
inflammatory cells. The inflamed synovium and fluid can damage the cartilage and
underlying bone.
No one knows what causes arthritis, though scientists have
uncovered a host of clues. Something can be done to manage most forms of
arthritis, but it's very important that a correct diagnosis is established
early. Most therapies work best when started early in the disease process. You
can read more specific information under Types of Arthritis.
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