Proton Pump Inhibitors (PPIs)

Drug Name
Proton Pump Inhibitors (PPIs)

Brand Name(s)
Esomeprazole (Nexium®), Lansoprazole (Prevacid®), Omeprazole (Losec®), Pantoprazole (Pantoloc®, Tecta®), Rabeprazole (Pariet®) Vimovo® is a combination of the NSAID naproxen with esomeprazole in one t

Drug Class
NSAIDs and COXIBs

PPIs are a class of medications that work by stopping your stomach from producing ulcer-causing acid. When taken with an NSAID, PPIs reduce the risk of developing ulcers and promote ulcer healing.


This information was written in November 2017, with expert advice from:

Jason Kielly, B.Sc. (pharm.), Pharm.D.
Assistant Professor, School of Pharmacy, Memorial University of Newfoundland
Clinical Pharmacist, Rheumatic Health Program, Eastern Health

This information was last updated in December 2021 by:

Alan Low, B.Sc. (pharm.), Pharm. D., ACPR, FCSHP, CCD, RPh
Clinical Associate Professor, Faculty of Pharmaceutical Sciences, UBC
Co-Founder and Executive Director, Medicines Access Coalition – BC
​Primary Care Pharmacist, VancouverGo Back to Drug Index